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"Innovations in
Medical/Bio-technology"
ABBY Award Winner
Osmetech’s
eSensor® Technology to Detect Nucleic Acids on a Microarray:
Osmetech Molecular Diagnostics provides cutting-edge,
cost-effective molecular diagnostic technologies and tools
that enable a broader range of hospitals and laboratories to
offer molecular diagnostic services for improved patient care.
The company’s eSensor® is the first FDA-cleared DNA microarray
product based on electrochemical detection of DNA
hybridization for molecular diagnostics and personalized
medicine. eSensor® employs a novel technology that offers
tremendous potential towards miniaturization of DNA diagnostic
systems. The eSensor® device consists of an inexpensive
printed circuit board (PCB) microarray chip that contains 72
electrodes; each is a DNA micro-sensor coated with specific
DNA molecules with unique sequences. The device allows direct
electronic measurement of a patient’s DNA at the surface of
electrodes for genotype analysis. The device also employs
another novel technology -- microfluidic Lab-on-a-chip, to
reduce test time from 2 hours to 30 minutes. As the demand for
and acceptance of molecular diagnostic tests multiplies, so
does the rate of testing decentralization. The movement of
this testing into the clinical labs of mid-size hospitals
requires greater simplicity, flexible testing capabilities,
and cost-effectiveness. The eSensor’s use of electrochemical
detection schemes obviates the need for conventionally large
and expensive optical scanners. |